Welcome to the 1001 Genomes Project
The 1001 Genomes Vision
The 1001 Genomes Project, launched at the beginning of 2008, has as a goal to discover the whole-genome sequence variation in 1001 strains (accessions) of the reference plant Arabidopsis thaliana. The resulting information is paving the way for a new era of genetics that identifies alleles underpinning phenotypic diversity across the entire genome and the entire species. Each of the accessions in the 1001 Genomes project is an inbred line with seeds that are freely available from the stock centre to all our colleagues. Unlimited numbers of plants with identical genotype can be grown and phenotyped for each accession, in as many environments as desired, and so the sequence information we collect can be used directly in association studies at biochemical, metabolic, physiological, morphological, and whole plant-fitness levels. The analyses enabled by this project will have broad implications for areas as diverse as evolutionary sciences, plant breeding and human genetics.
The complete genome sequences of over 80 accessions have been released in early 2010 by the Max Planck Institute. There are commitments for the remaining accessions, primarily from the Salk Institute, the Gregor Mendel Institute and Monsanto, and we are hoping for completion of the 1001 Genomes project in 2012.
The data from the Max Planck Institute can now be cited:
Schneeberger, K., Ossowski, S., Ott, F., Klein, J. D., Wang, X., Lanz, C., Smith, L. M., Cao, J., Fitz, J., Warthmann, N., Henz, S. R., Huson, D. H., and Weigel, D. (2011) Reference-guided assembly of four diverse Arabidopsis thaliana genomes. Proc. Natl. Acad. Sci. USA 108, 10249-10254.
Cao, J., Schneeberger, K., Ossowski, S., Günther, T., Bender, S., Fitz, J., Koenig, D., Lanz, C., Stegle, O., Lippert, C., Wang, X., Ott, F., Müller, J., Alonso-Blanco, C., Borgwardt, K., Schmid, K. J., and Weigel, D. (2011) Whole-genome sequencing of multiple Arabidopsis thaliana populations. Nature Genetics 43, 956–963 (2011).
Progress as of November 15, 2011:
Commitments: 1001
Sequencing underway: 24
Finished genomes: 503
Released genomes: 471